Wuhan Fine Biotech Co., Ltd.'s AP3B2 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, Precipitation, ELISA, Immunoprecipitation, and Western Blot. The AP3B2 antibody was generated using AP3B2 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals